Endometriosis Explained Episode 7
๐ฅHow Is Endometriosis Treated?
There is no single treatment that is right for every woman with endometriosis.
Treatment should be individualized according to:
• Severity and pattern of symptoms
• Desire for pregnancy now or in the future
• Age and ovarian reserve
• Extent and location of disease
• Previous treatment response
• Side-effect profile and personal preferences.
1. Pain relief
Simple analgesics and anti-inflammatory medications may help control symptoms, particularly during painful episodes.
2. Hormonal treatment
For women who are not trying to conceive immediately, hormonal suppression is a major treatment option and may be used long-term for symptom control.
Options may include:
• Combined hormonal contraceptives
• Progestins
• Levonorgestrel intrauterine system
• GnRH agonists or antagonists in selected patients.
• Add-back therapy when appropriate
The choice should be made through shared decision-making, because different options have different benefits, risks and side-effects.
3. Give treatment enough time
One important update from current guidelines:
Do not label a hormonal treatment as a failure too early.
If side-effects are tolerable, treatment should usually be continued for at least 3 months before its effectiveness is properly assessed.
4. Surgery
Surgery may be considered when there is:
• Persistent or severe pain
• Organ dysfunction
• Extensive disease
• Endometrioma in selected cases
• Infertility where surgery may offer benefit.
But surgery is not automatically required simply because endometriosis is present.
The surgical plan should depend on the patient's goals, symptoms and complexity of disease.
5. Fertility treatment
If pregnancy is the priority, the treatment pathway changes.
Hormonal suppression may improve pain, but it does not improve fertility in women with endometriosis-associated infertility.
๐ค Fertility evaluation, surgery in selected cases, IUI or IVF may be considered depending on age, ovarian reserve, tubal status and other factors.
๐ Guideline Pearl
For patients not seeking immediate pregnancy, hormonal therapy should be offered and may be used long-term for symptom control. Treatment choice should be individualized not prescribed as a one-size-fits-all approach.
๐ The goal is not only to treat the lesions. It is to treat the woman, her symptoms, her fertility plans and her quality of life.
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