When Do We REALLY Need Pregnancy Support (Progesterone) Medications? 

“Pregnancy stabilizers” or progesterone supplements are widely used — but medically, they are NOT needed for every pregnancy.

📌 According to international guidelines (ACOG, RCOG, ESHRE):

✅ Progesterone IS recommended in specific situations only:

1️⃣ Threatened miscarriage

• Vaginal bleeding in early pregnancy

• With a confirmed intrauterine pregnancy

• Especially in women with a history of previous miscarriage

2️⃣ Recurrent pregnancy loss

• Women with ≥2–3 previous miscarriages

• Progesterone may improve live birth rates in selected cases

3️⃣ Assisted reproduction (IVF / ICSI)

• Luteal phase support is standard of care

• Progesterone is essential until placental hormone production is established

4️⃣ Proven luteal phase deficiency

• Diagnosed clinically, not routinely screened

• Selected cases only

⚠️ Progesterone is NOT routinely needed for:

• Every early pregnancy

• Mild cramps without bleeding

• Normal pregnancies with no risk factors

• “Just in case” use without medical indication

🧠 Important medical facts:

• Most miscarriages are caused by chromosomal abnormalities — progesterone cannot prevent these.

• Overuse of medications does NOT guarantee pregnancy continuation.

• Treatment should be evidence-based, not fear-based.

🩺 Practical guidance:

• Ultrasound confirmation of an intrauterine pregnancy is essential

• Dosage, route (oral, vaginal, injection), and duration must be individualized

• Follow-up is more important than medication alone

✨ Key message:

Progesterone can be life-saving in the RIGHT patient — but unnecessary in many others.

Correct diagnosis and personalized care always come first.

Dr Rabab Cares 🤍

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