PMOS Explained  Episode 3

👏 PMOS Phenotypes & Different Presentations

Not every woman with PMOS looks the same.

PMOS can present in different ways depending on which features are present:

• Ovulatory dysfunction
• Hyperandrogenism
• Polycystic ovarian morphology (PCOM)

Based on these features, PMOS can be classified into four main phenotypes.

💥 Phenotype A — Classic Phenotype

Hyperandrogenism + Ovulatory Dysfunction + Polycystic Ovarian Morphology

All three features are present.

💥 Phenotype B — Classic Non-PCOM Phenotype

Hyperandrogenism + Ovulatory Dysfunction

Polycystic ovarian morphology is not required for this phenotype.

💥 Phenotype C — Ovulatory Phenotype

Hyperandrogenism + Polycystic Ovarian Morphology

Ovulation is generally preserved.

💥 Phenotype D — Non-Hyperandrogenic Phenotype

Ovulatory Dysfunction + Polycystic Ovarian Morphology

Without clinical or biochemical hyperandrogenism.

🤗 Why Do Women With PMOS Have Different Symptoms?

This explains why two women with PMOS may have completely different presentations.

• One may mainly experience irregular menstrual periods.
• Another may struggle with acne or excessive hair growth.
• Another may experience fertility challenges.
• And another may have metabolic abnormalities, even without obvious symptoms.

The combination and severity of symptoms can vary considerably from one woman to another.

🤔 The Important Message

PMOS is not one single picture.

It represents a spectrum of reproductive, hormonal, and metabolic features.

Management should therefore be individualized according to:

• Symptoms and clinical presentation
• Metabolic risk
• Menstrual and ovulatory function
• Fertility goals
• Overall health

Different presentations require individualized care.

🌸 Coming Next — Episode 4

Hormonal and Metabolic Changes in PMOS

Understanding what happens behind the symptoms.

Dr Rabab Cares ❤️

#DrRababCares #PMOS #PCOS #PMOSExplained #WomensHealth #HormonalHealth #MetabolicHealth #OvarianHealth #Hyperandrogenism #IrregularPeriods