PMOS Explained 

Episode 6

PMOS and Fertility

One of the biggest fears women have after being diagnosed with PMOS is:

“Will I be able to get pregnant?”

The answer is:

Yes  many women with PMOS become pregnant naturally or with treatment.

PMOS does not automatically mean infertility.

How does PMOS affect fertility?

The main fertility problem in PMOS is often irregular or absent ovulation.

If ovulation does not happen regularly, it becomes more difficult to predict the fertile window and pregnancy may take longer.

Fertility depends on more than PMOS alone

Other factors also matter, including:

• Age
• Partner’s semen analysis
• Tubal patency
• Weight and metabolic health
• How regularly ovulation occurs
• Other reproductive conditions

Treatment options

For women with anovulatory infertility due to PMOS and no other infertility factors, letrozole is currently recommended as the first-line medication for ovulation induction.

Other options may include:

• Clomiphene citrate
• Metformin in selected women
• Gonadotrophins
• And, when needed, assisted reproductive treatments such as IVF

Treatment should always be individualized.

The important message

PMOS may make pregnancy more difficult for some women but it does not mean pregnancy is impossible.

With proper assessment and the right treatment plan, many women with PMOS can successfully conceive.

Next episode:
PMOS through different life stages.

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